Can Lion’s Mane Mushroom Help With Anxiety?

Can Lion’s Mane Mushroom Help With Anxiety?

In today's fast-paced and stressful world, anxiety has become a prevalent issue. 

Many individuals are seeking natural remedies to mitigate anxiety symptoms and enhance overall well-being. 

One such remedy that is gaining popularity is lion's mane mushroom (Hericium erinaceus). 

Let's delve into the potential benefits of lion's mane mushroom for anxiety relief and its role in promoting mental wellness.

Understanding anxiety 

Anxiety is a multifaceted mental health condition characterised by persistent feelings of worry, fear, and unease. 

It can disrupt daily life, affecting work performance, relationships, and overall quality of life. 

While therapy and medication are available as treatment options, some individuals are turning to alternative approaches such as natural supplements.

How is anxiety treated?

Anxiety is often treated using a combination of medication and therapy. 

Medications like antidepressants can help manage symptoms. Therapy, such as behavioural therapy, can teach coping strategies and improve functioning..

These traditional anxiety treatments can be highly effective. Therapy, like cognitive-behavioural therapy (CBT), helps identify and change negative thought patterns, and medications, like selective serotonin reuptake inhibitors (SSRIs), can reduce anxiety symptoms. 

However, effectiveness varies from person to person, and anxiety medications do come with unwanted side effects. 

What are the main effects of lion’s mane?

Lion’s mane has become very popular among people with anxiety. 

This is largely thanks to its cognitive benefits including its ability to increase NGF (nerve growth factor) levels and promote neurogenesis (growth of new brain cells). 

These properties mean that many people who use lion’s mane experience:

  • Clarity of thought
  • Enhanced memory
  • Enhanced focus
  • Enhanced cognition
  • Increased energy

The unseen benefits of lion’s mane are even more profound and include: 

You’d be wise not to expect instant results with lion’s mane supplements, however. Clinical studies done with lion’s mane are typically done over at least two months of use.

Can lion's mane mushroom help with anxiety?

Several studies suggest that lion's mane mushroom may have an impact on anxiety symptoms and overall mental well-being. 

This study looked at the effects of lion’s mane on menopause, depression, sleep quality, and general complaints among 30 women.  

The subjects were randomly assigned to either the lion’s mane group or the placebo group, and for 4 weeks, they consumed either lion’s mane cookies or placebo cookies. 

The results showed that after taking lion’s mane cookies , the scores for depression and general complaints were significantly lower compared to before. 

Additionally, in terms of specific complaints, the lion’s mane group had significant improvements in  concentration, irritation, and anxiety scores.

These findings suggest that lion’s mane intake has the potential to reduce depression and anxiety, possibly due to a mechanism beyond its known effect on NGF synthesis.

Another experiment, conducted on mice, revealed that lion's mane extract demonstrated anxiolytic effects by reducing anxiety-like behaviours and promoting a sense of calm. 

And this one found that consuming lion's mane prevents cognitive dysfunction in healthy adults. 

Although further research is necessary to confirm these effects, the initial findings are promising.

Potential benefits of lion's mane for anxiety

The potential benefits of lion's mane for individuals with anxiety include:

  • Reduced anxiety symptoms: Lion's mane has been found to have anxiolytic properties, which means it may help reduce anxiety symptoms and promote relaxation.
  • Improved mood: Lion's mane may have mood-enhancing effects, potentially reducing feelings of depression or low mood commonly associated with anxiety.
  • Enhanced cognitive function: Lion's mane has been studied for its potential to improve cognitive function, including memory and concentration. This can be particularly helpful for individuals with anxiety, who may experience difficulties in these areas due to racing thoughts or excessive worry.
  • Neuroprotective effects: Lion's mane contains compounds that can support the health of nerve cells and protect against oxidative stress, potentially benefiting individuals with anxiety-related neurodegeneration.

While lion's mane shows promise as a natural remedy for anxiety, it's important to remember that effects can take a few weeks to manifest and it may not work for everyone. 

How does lion's mane mushroom work?

Lion's Mane mushroom contains bioactive compounds believed to contribute to its potential therapeutic effects. 

These compounds include hericenones and erinacines, which have been found to stimulate the production of nerve growth factors (NGFs) in the brain. 

NGFs play a vital role in the growth, maintenance, and repair of nerve cells, promoting neuroplasticity and supporting overall brain health.

How to take lion's mane mushroom for anxiety

When it comes to consuming lion’s mane, you have a number of options. 

Eat it

Of course, you can pick and eat lion’s mane mushrooms and it’s actually quite nice. Its texture can be quite tough so it’s best to cook - ideally pan fry - beforehand. 


Capsules containing dried lion’s mane powder or an extract are very convenient and accurate ways of taking lion’s mane. One convenient option is our popular Cognitive Enhancer Lion's Mane Capsules

These potent capsules contain pure lion's mane mushroom extract, ensuring a convenient and standardised dosage for consistent results. 


Dried lion’s mane powder is a versatile way to add the mushroom to smoothies or various dishes. 


Alcohol-based extracts offer a way to consume concentrated lion’s mane easily and effectively. These tinctures can be quite potent and are great for adding to coffee, tea or other drinks. 

By integrating lion's mane mushroom into your wellness regimen, you can support your journey towards anxiety relief and improved mental well-being.

Lion’s mane vs anxiety medication 

There are several potential benefits of using a natural treatment option such as lion's mane mushroom instead of traditional ADHD medication:

Reduced Side Effects: Unlike many traditional anxiety medications that may come with a range of side effects, lion's mane mushroom is generally considered safe and well-tolerated, making it an appealing option for those seeking a natural approach with minimal negative effects.

Cognitive Function Support: Anxiety often takes a toll on cognitive function, leading to difficulties in concentration, memory, and decision-making.

By promoting the production of nerve growth factors, such as the crucial protein known as nerve growth factor (NGF), lion’s mane may support brain health and aid in restoring cognitive function. Something that commonly prescribed anti-anxiety medication doesn’t.

Anti-Inflammatory and Neuroprotective Effects: Inflammation in the brain has been linked to the development and exacerbation of anxiety symptoms.

Lion's mane contains bioactive compounds that possess anti-inflammatory properties, potentially reducing oxidative stress and inflammation in the brain. 

Complementary Therapy Option: Lion's mane mushroom can be used alongside other anxiety management strategies, including therapy and lifestyle modifications.

Combining lion's mane with techniques like mindfulness, exercise, or counselling may provide a more holistic approach to anxiety management, addressing the condition from various angles.


Anxiety can significantly impact our lives, but natural remedies like lion's mane mushroom offer a potential solution. 

Studies have found that compounds in lion's mane may have potential benefits for cognitive function and overall brain health, and anecdotal evidence suggest it may be helpful for certain anxiety symptoms, but more research is needed to fully understand the effects on anxiety specifically.

As a natural treatment option with limited side effects, lion's mane mushrooms may be useful in conjunction with other therapies, such as cognitive behavioural therapy, to provide a more comprehensive treatment plan for individuals with anxiety.

If you're interested in trying lion's mane, we stock one of the strongest standardised lion’s mane extracts on the market here

This article was written strictly for educational purposes and is not intended to offer medical advice, diagnosis, or treatment of any kind.

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